TY - JOUR AU1 - Yeoh, Aaron AU2 - Kulkarni, Chiraag AU3 - Ryan, Emily AU4 - Berry, Gerald AU5 - Triadafilopoulos, George AB - Digestive Diseases and Sciences https://doi.org/10.1007/s10620-023-07982-6 STANFORD MULTIDISCIPLINARY SEMINARS Severe Diarrhea and Weight Loss Due to Protein‑Losing Enteropathy: Don’t Pass Up the PAS Stain 1 1 2 2 1 Aaron Yeoh  · Chiraag Kulkarni  · Emily Ryan  · Gerald Berry  · George Triadafilopoulos Accepted: 24 April 2023 © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2023 Case Presentation and Evolution cancer in his uncle with no other known family history of other gastrointestinal disorders. A 48-year-old male with a history of polysubstance use dis- At the time of admission to our center, his examination order was evaluated for complaints of diarrhea, abdominal was notable for a cachectic male with diffuse muscle wast- pain, and weight loss of greater than one year duration. He ing, a distended abdomen diffusely tender to palpation, reported that approximately 18 months before presentation, 1 + lower extremity edema, and pruritic papules on his trunk he noted the insidious onset of post-prandial non-bloody and extremities (Fig. 1). Cardiopulmonary examination was diarrhea that occurred shortly after meals progressing to > 20 within normal limits. loose bowel movements daily. He subsequently developed Initial laboratory studies showed a WBC of 9.2, Hgb 6.3 diffuse cramping abdominal pain, a pruritic rash on his (low), TI - Severe Diarrhea and Weight Loss Due to Protein-Losing Enteropathy: Don’t Pass Up the PAS Stain JF - Digestive Diseases and Sciences DO - 10.1007/s10620-023-07982-6 DA - 2023-08-01 UR - https://www.deepdyve.com/lp/springer-journals/severe-diarrhea-and-weight-loss-due-to-protein-losing-enteropathy-don-bc0GIQ9xyi SP - 3249 EP - 3253 VL - 68 IS - 8 DP - DeepDyve ER -