TY - JOUR AU - Graham‐Brown, R. AB - Case studies of alitretinoin in the treatment of severe chronic hand eczema • J. English et al. Case study 3 – A 41-year-old male with hyperkeratotic changes to the hands and feet R. Graham-Brown Department of Dermatology, University Hospitals of Leicester, Leicester, UK A 41-year-old male patient initially presented to his received multiple short, tapering courses of systemic dermatologist with hyperkeratotic changes to the prednisolone with mixed success. Although the steroids hands. On further examination he was also found to reduced the inflammation and dryness, as soon as he have severe foot eczema. withdrew treatment the disease returned with the same Foot eczema can be an extremely debilitating disease, severity. causing the patient extreme difficulties in daily life. After tacrolimus 0.1% ointment treatment proved Although there is less psychological impact, as com- unsuccessful, the patient was offered a course of PUVA. pared to the highly visible nature of hand eczema the This provided a partial response, but was not considered disease is ‘hidden’ from other people, walking and sufficient by the patient to justify the time spent wearing socks and shoes can be very painful. For this travelling to the treatment centre. A subsequent course patient, the disease on TI - Case study 3 – A 41‐year‐old male with hyperkeratotic changes to the hands and feet JF - Clinical and Experimental Dermatology DO - 10.1111/j.1365-2230.2010.04006_4.x DA - 2011-03-01 UR - https://www.deepdyve.com/lp/oxford-university-press/case-study-3-a-41-year-old-male-with-hyperkeratotic-changes-to-the-bWEDsnrHhf SP - 7 EP - 7 VL - 36 IS - s1 DP - DeepDyve ER -