TY - JOUR
AU - Leung, T.F.
AB - Research letter Eczema susceptibility and composition of diversity index was used to measure the microbial diversity of faecal microbiota at 4 weeks of age: a pilot the stool samples. Briefly, this index was calculated by the study in Chinese infants formula Σlog(p)p, where p denotes the relative abundance of species. It incorporates the richness and evenness of species DOI: 10.1111/bjd.14205 in the community, typically with a value between 1
5 and 3
5. Differences in this index and different bacterial taxa at the DEAR EDITOR, Early-life microbial exposure plays an important genus level between eczema and controls at 9 months were part in the development of the immune system, reducing the analysed by the Mann–Whitney U-test. Statistical significance likelihood of allergy. Several studies have investigated alter- was defined as P < 0.05. ations in the relative abundance of bacterial species in the gut Table S1 describes infants whose stool samples were sub- microbiota. Escherichia coli has been reported to be more abun- jected to NGS. Owing to insufficient DNA, five controls were dant in infants who develop atopic eczema than in healthy excluded; therefore, 15 cases and 10 controls were sequenced. infants. Compared with controls, a reduced abundance of Bifi- All 
TI - Eczema susceptibility and composition of faecal microbiota at 4 weeks of age: a pilot study in Chinese infants
JO - British Journal of Dermatology
DO - 10.1111/bjd.14205
DA - 2016-04-01
UR - https://www.deepdyve.com/lp/oxford-university-press/eczema-susceptibility-and-composition-of-faecal-microbiota-at-4-weeks-bVaMz0Dn2p
SP - 898
EP - 900
VL - 174
IS - 4
DP - DeepDyve
ER -