TY - JOUR
AU - Zare, Richard N.
AB - A two‐step laser desorption lamp ionization source coupled to an ion trap mass spectrometer (LDLI‐ITMS) has been constructed and characterized. The pulsed infrared (IR) output of an Nd:YAG laser (1064 nm) is directed to a target inside a chamber evacuated to ~15 Pa causing desorption of molecules from the target's surface. The desorbed molecules are ionized by a vacuum ultraviolet (VUV) lamp (filled with xenon, major wavelength at 148 nm). The resulting ions are stored and detected in a three‐dimensional quadrupole ion trap modified from a Finnigan Mat LCQ mass spectrometer operated at a pressure of ≥ 0.004 Pa. The limit of detection for desorbed coronene molecules is 1.5 pmol, which is about two orders of magnitude more sensitive than laser desorption laser ionization mass spectrometry using a fluorine excimer laser (157 nm) as the ionization source. The mass spectrum of four standard aromatic compounds (pyrene, coronene, rubrene and 1,4,8,11,15,18,22,25‐octabutoxy‐29H,31H‐phthalocyanine (OPC)) shows that parent ions dominate. By increasing the infrared laser power, this instrument is capable of detecting inorganic compounds. Copyright © 2015 John Wiley & Sons, Ltd.
TI - Laser desorption lamp ionization source for ion trap mass spectrometry
JO - Journal of Mass Spectrometry (Incorp Biological Mass Spectrometry)
DO - 10.1002/jms.3509
DA - 2015-01-01
UR - https://www.deepdyve.com/lp/wiley/laser-desorption-lamp-ionization-source-for-ion-trap-mass-spectrometry-bJqzP0NAgE
SP - 160
EP - 164
VL - 50
IS - 1
DP - DeepDyve
ER -