TY - JOUR
AU1 - Spielberger, Ricardo, T.
AU2 - Falleroni, Marc, J.
AU3 - Coene, Amy, J.
AU4 - Larson, Richard, A.
AB - Abstract The use of granulocyte transfusions during amphotericin B treatment of invasive fungal infections in granulocytopenic patients is controversial because of concern about pulmonary complications from leukostasis. Moreover, the administration of granulocyte-macrophage colony-stimulating factor (GM-CSF) to patients with active infections has been questioned because of reports that this cytokine inhibits neutrophil migration into areas of inflammation. We report a case in which the combined use of amphotericin B, granulocyte transfusions, and GM-CSF was safe and life-saving in a pancytopenic patient with disseminated fusarium infection. Histologic evidence of the migration of neutrophils into an area of active infection was found. This content is only available as a PDF. © 1993 by The University of Chicago
TI - Concomitant Amphotericin B Therapy, Granulocyte Transfusions, and GM-CSF Administration for Disseminated Infection with Fusarium in a Granulocytopenic Patient
JF - Clinical Infectious Diseases
DO - 10.1093/clind/16.4.528
DA - 1993-04-01
UR - https://www.deepdyve.com/lp/oxford-university-press/concomitant-amphotericin-b-therapy-granulocyte-transfusions-and-gm-csf-bBnJGCxWML
SP - 528
EP - 530
VL - 16
IS - 4
DP - DeepDyve
ER -