TY - JOUR
AU - Reimann, Hobart A.
AB - RICKETTSIA OF ROCKY MOUNTAIN SPOTTED FEVER IN THE BRAIN OF THE INFECTED GUINEA-PIG HOB ART A. REI M: ANN * From the Pathological Inst£tute of the German University, Prague, Czechoslovak£a From the studies of vVolbach 1 and Nicholson 2 it is evident that Rickettsia associated with Rocky Mountain spotted fever (Dermacen­ troxenus rickettsi) are invariably found only in tissues showing the char­ acteristic vascular lesions described in the literature. Wolbach states that the central nervous system in animals suffering from Rocky Mountain spotted fever shows no lesions attributable to that disease and one must therefore assume that this tissue contains no parasites. It is known, however, that the brain tissue of infected guinea-pigs serves as good material for the experimental transfer of Rocky Mountain spotted fever from one guinea-pig to another. Brein1 has shown by titration experi­ ments that the brain of an infected guinea-pig, and also the testes, con­ tains approximately 100,000 infectious doses. Therefore a tissue which is apparently free from organisms (brain) and a tissue (testes) in which the organisms are present in abundance are equally infectious. The blood of animals suffering from the disease contains Rickettsia and it is also highly infectious. According to Connor/ 
TI - Rickettsia of Rocky Mountain Spotted Fever in the Brain of the Infected Guinea-Pig
JF - The Journal of Infectious Diseases
DO - 10.1093/infdis/43.1.93
DA - 1928-07-01
UR - https://www.deepdyve.com/lp/oxford-university-press/rickettsia-of-rocky-mountain-spotted-fever-in-the-brain-of-the-bAD2Sozll5
SP - 93
EP - 96
VL - 43
IS - 1
DP - DeepDyve
ER -