TY - JOUR AU - Karselis, Terence C. AB - Vol.7 1 . No. 4 LETTERS TO THE EDITOR sitivity of a given system to heparin has suggested that this represents adequate from the plasma as soon as possible, been established, the literature would heparinization even though the APTT keeping the test tube stoppered, and suggest adequate heparinization is re­ result compared to the upper limits of performing the coagulation procedure flected by a prolongation of the APTT normal would suggest underhepariniza- within one hour after drawing the blood. 2 to 2 /i the upper limits of normal. Cer­ tion. Also, the nature of the activator (i.e., tainly the values obtained by one instru­ ellagic acid, kaolin, etc.) and the ratio of As Dr. Hattersley points out, there ment reagent combination cannot be citrate to plasma must be considered. are a number of tests available for extrapolated to an entirely different in­ monitoring heparin therapy, includ­ I would like to thank Dr. Hattersley strument reagent combination. ing the Activated Coagulation Time for emphasizing several extremely (ACT). Certainly any of these tests critical points, which should be kept in More recent work would indicate that can be effectively used to monitor mind by all coagulation laboratories and the use of TI - Ion-selective Electrode JF - American Journal of Clinical Pathology DO - 10.1093/ajcp/71.4.481 DA - 1979-04-01 UR - https://www.deepdyve.com/lp/oxford-university-press/ion-selective-electrode-b66yWVN5gT SP - 481 EP - 481 VL - 71 IS - 4 DP - DeepDyve ER -