TY - JOUR
AU - Li, Debiao
AB - The use of off-resonance methods in interventional MRI may be valuable since active devices that provide positive signal enhancements are currently not approved for human use. This study investigated the capacity of a low flip angle steady-state free precession (FLAPS) method for generating off-resonance positive contrast surrounding a susceptibility-shifted endomyocardial Stiletto catheter in excised swine hearts and in live swine. Consistent with theory, discernable positive contrast surrounding the interventional device was visualized under ex-vivo (CNR of 24 ± 2.1 in the left ventricular (LV) chamber and 18 ± 2.7 in LV myocardium) and in-vivo conditions (CNR of 22 ± 3.9 in aorta, 16 ± 4.1 in the LV chamber and 13 ± 0.9 in LV myocardium). The findings show that off-resonance imaging with the FLAPS method may be used for passive device visualization with positive contrast. Further studies are necessary prior to clinical translation.
TI - Off-resonance positive contrast imaging of a passive endomyocardial catheter in swine
JF - Physics in Medicine and Biology
DO - 10.1088/0031-9155/53/13/N02
DA - 2008-07-07
UR - https://www.deepdyve.com/lp/iop-publishing/off-resonance-positive-contrast-imaging-of-a-passive-endomyocardial-aNunENEnhb
SP - N249
VL - 53
IS - 13
DP - DeepDyve
ER -