TY - JOUR
AU - EDWARDS, R. G.
AB - IMMUNOLOGY OF CONCEPTION AND PREGNANCY R. G. Edwards husband (Halpern, Ky & Robert, 1967); and women with Addison's or Cushing's disease can produce autoantibodies that destroy their own ovarian follicles (Irvine, Chan, Scarth, Kolb, Hartog, Bayliss & Drury, 1968). These examples provide data and ideas on the mode of action of potential IMMUNOLOGY OF CONCEPTION contraceptive methods and we will return to them later. Three general points must first be made about immuno- AND PREGNANCY logical aspects of reproduction. First, many tissues involved in reproductive functions are separated from the circulation by a basement membrane, although the female reproductive R. G. EDWARDS D.Sc. tract is exposed to fluid coming via the fimbria of the oviduct. Some of these membranes are highly impermeable to immuno- Physiological Laboratory globulins (reviewed by Edwards, 1969c). For example, University of Cambridge the blood-testis barrier is usually traversed by only small amounts of immunoglobulins (Johnson & Setchell, 1968). 1 Antibodies against testis and spermatozoa In many species, the secretions of the uterus and cervix also a Autoimmune aspermatogencsis contain only small amounts of immunoglobulins and serum b Agglutination of spermatozo a in men proteins. In contrast, follicular fluid appears to be largely c Antibodies against 
TI - IMMUNOLOGY OF CONCEPTION AND PREGNANCY
JF - British Medical Bulletin
DO - 10.1093/oxfordjournals.bmb.a070746
DA - 1970-01-01
UR - https://www.deepdyve.com/lp/oxford-university-press/immunology-of-conception-and-pregnancy-aJZKxAeFBd
SP - 72
EP - 78
VL - 26
IS - 1
DP - DeepDyve
ER -