TY - JOUR AU - HATA, J-I AB - SUMMARY Distinct expression pattern of CD10 molecules during B cell activation was analysed using in vivo and in vitro systems. By two-colour flowcytometrical analysis, CD10 was found to be expressed at a specificstage of in vivo activating B cells. The expression of CD10 during B cell activation appeared to be unique from that of other activation-related B cell antigens including L29, MA6, OKT9 and OKT10. Although the expression of CD10 was associated with that of the activation-related B cell antigens, CD 10+ B cells could be separated in the distinct fractions to those expressing other activation-related B cell antigens when fractionated by cell gravity. In particular, certain CD10+ B cells were detected positive for the resting B cell antigen, L30. In vitro studies revealed that CD10+ B cells arose from CD10- B cells at an early step of B cell activation, and disappeared lately when activated by Staphylococcus aureus Cowan I. 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This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model) TI - Characterization of the common acute lymphoblastic leukaemia antigen (CD10) as an activation molecule on mature human B cells JO - Clinical & Experimental Immunology DO - 10.1111/j.1365-2249.1990.tb08090.x DA - 2008-06-28 UR - https://www.deepdyve.com/lp/oxford-university-press/characterization-of-the-common-acute-lymphoblastic-leukaemia-antigen-XtwFi6Jdb0 SP - 322 EP - 327 VL - 79 IS - 3 DP - DeepDyve ER -