TY - JOUR
AU - Bellas, Carmen
AB - NONGYNECOLOGIC CYTOPATHOLOGY Diagnostic Value of JC/BK Virus Antibody Immunohistochemistry Staining in Urine Samples from Posttransplant Immunosuppressed Patients in Relation to Polyomavirus Reactivation Rosario Sanchez Yuste, M.D., Carolina Frías, Ph.D., Ana López, M.D., Carlos Vallejo, Ph.D., Paloma Martín, Ph.D., and Carmen Bellas, Ph.D. Objective Conclusion To compare the diagnostic value of cytology and immuno- The main advantage of IHS is that it allowed confirmation histochemistry staining (IHS) of urine samples for polyo- of BKV infection diagnosis in urine samples. IHS detected mavirus reactivation diagnosis. more BKV-infected cells in samples with few positive urothelial cells, which would have gone undetected if only Study Design Papanicolaou staining had been used as the BKV screening Sixty-eight urine samples col- method. Urine samples testing lected from 18 immunosup- for BKV by both techniques pressed patients were analyzed will improve diagnosis in IHS confirms Papanicolaou by Papanicolaou and IHS asymptomatic patients, allow- staining findings, helping to with a JC/BK virus–specific ing early therapeutic inter- diagnose doubtful cases or even monoclonal antibody. vention and a better clinical outcome. (Acta Cytol 2008; allowing diagnosis of negative Results 52:191–195) cases after routine staining. Overall, polyomavirus BK (BKV) was positive in 11 of Keywords: BK virus; cytol- 18 patients 
TI - Diagnostic Value of JC/BK Virus Antibody Immunohistochemistry Staining in Urine Samples from Posttransplant Immunosuppressed Patients in Relation to Polyomavirus Reactivation
JF - Acta Cytologica
DO - 10.1159/000325478
DA - 2011-01-01
UR - https://www.deepdyve.com/lp/karger/diagnostic-value-of-jc-bk-virus-antibody-immunohistochemistry-staining-XKa8J5ISLe
SP - 191
EP - 195
VL - 52
IS - 2
DP - DeepDyve
ER -