TY - JOUR
AU - Jacobs, Brian R.
AB - Background: Intraluminal occlusion is common in children withcentral venous catheters (CVCs). Although multiple factors predispose CVCs toocclusion, reflux of blood is frequently implicated. We hypothesized that useof either a single-valve or positive-pressure-valve needleless connectordevice would reduce CVC occlusion rates in comparison to a standard device. Wefurther hypothesized that saline would be as effective as heparinized salineflush in preventing occlusion and infection. Methods: CVC lumens wereprospectively capped with 1 of 3 needleless connector devices in a 4-groupdesign. Group 1 lumens were capped with a standard device, group 2 with asingle-valve device, group 3 with a positive-pressure-valve device flushedwith heparinized saline, and group 4 with a positive-pressure-valve deviceflushed with saline. Data were obtained regarding occlusion and infectionrates and user satisfaction. Results: Three hundred sixty childrenwith 599 CVC lumens completed the study. Complete occlusion occurred in 19/150(12.7%) lumens in group 1 in comparison to 2/150 (1.3%) in group 2, 5/149(3.4%) in group 3, and 6/150 (4%) in group 4 (p < .05). There wasa trend toward a 2-fold greater infection rate in group 4. User satisfactionwas higher in groups 2, 3, and 4 than group 1 (p < .05).Conclusions: CVCs capped with a single-valve orpositive-pressure-valve needleless connector device have lower completecatheter occlusion rates than those capped with a standard device. Heparinizedsaline flush affords no advantages over saline in reducing occlusion rate;however, there was a trend toward lower infection rate with the use ofheparinized saline.
TI - The Impact of Needleless Connector Device Design on Central VenousCatheter Occlusion in Children: A Prospective, Controlled Trial
JF - Journal of Parenteral and Enteral Nutrition
DO - 10.1177/014860710603000285
DA - 2006-03-01
UR - https://www.deepdyve.com/lp/wiley/the-impact-of-needleless-connector-device-design-on-central-XKL0rf2iXe
SP - 85
EP - 90
VL - 30
IS - 2
DP - DeepDyve
ER -