TY - JOUR
AU - 
AB - CLOSED TIBIAL FRACTURES The Professional Medical Journal www.theprofesional.com ORIGINAL PROF-4328 DOI: 10.29309/TPMJ/18.4328 STUDY THE ROLE OF GENE SILENCING IN CERVICAL CANCER CELL LINE TO CONTROL CELL PROLIFERATION 1 2 3 Farah Deeba Khan , Ghazala Irshad , Samra Hafiz 1. MBBS, M.Phil (Biochemistry), ABSTRACT… Objectives: Cancer, the most complex group of genetic disorders results due PhD (Biochemistry) Professor to over expression or mutation of oncogenes/molecules involved in cell signaling pathways. Biochemistry Department KRAS is an oncogene that encodes a small GTPase protein with two isoforms KRasA & KRasB University College of Medicine & and is involved in the regulation of cell division. KRas is frequently found mutated in lung, Dentistry, The University of Lahore. pancreas, colorectal and many other cancers. Various studies have found that KRasB promotes 2. MBBS, M.Phil (Biochemistry) cell proliferation and inhibits apoptosis whereas KRasA has negligible role in cell proliferation Associate Professor or rather is involved in apoptosis at times. Several experiments have shown tumor growth Biochemistry Department inhibition by silencing KRas in various tumor models having a differential allelic expression. University College of Medicine & Dentistry, The goal of our study was to determine the possible differential role of KRas A and B on 
TI - GENE SILENCING
JO - The Professional Medical Journal
DO - 10.29309/tpmj/18.4328
DA - 2018-12-08
UR - https://www.deepdyve.com/lp/unpaywall/gene-silencing-XCHE2UJcQd
DP - DeepDyve
ER -