TY - JOUR AU - Yeh, Ming‐Yang AB - Previous work from our laboratory has led to the isolation of a monoclonal IgG2a mouse antibody, 3.2, which is specific for an antigen, 3.1, that is strongest expressed by a group of human melanomas. We have now demonstrated that this antibody can mediate antibody‐dependent cellular cytotoxicity (ADCC) to human melanoma cells expressing antigen 3.1, and that lymphocytes from human peripheral blood can be used as the source of K cells. A monoclonal IgG1 antibody, 3.1, to the same determinant of antigen 3.1 gave only weak and inconsistent ADCC. TI - Lymphocyte‐dependent antibodies to antigen 3.1, a cell‐surface antigen expressed by a subgroup of human melanomas JO - International Journal of Cancer DO - 10.1002/ijc.2910270305 DA - 1981-03-15 UR - https://www.deepdyve.com/lp/wiley/lymphocyte-dependent-antibodies-to-antigen-3-1-a-cell-surface-antigen-X8qDbX7Sgf SP - 281 EP - 285 VL - 27 IS - 3 DP - DeepDyve ER -