TY - JOUR AU1 - Ozben, Serkan AU2 - Guvenc, Tolga AU3 - Huseyinoglu, Nergiz AU4 - Sanivar, Hilal AU5 - Hanikoglu, Ferhat AU6 - Cort, Aysegul AU7 - Ozben, Tomris AB - Sleep Breath (2013) 17:1187–1192 DOI 10.1007/s11325-013-0822-7 ORIGINAL ARTICLE Low serum copeptin levels in patients with obstructive sleep apnea Serkan Ozben & Tolga Sinan Guvenc & Nergiz Huseyinoglu & Hilal Safak Sanivar & Ferhat Hanikoglu & Aysegul Cort & Tomris Ozben Received: 6 November 2012 /Revised: 22 January 2013 /Accepted: 31 January 2013 /Published online: 14 February 2013 Springer-Verlag Berlin Heidelberg 2013 Abstract severe (n=47) obstructive sleep apnea patients (0.42± Purpose Copeptin, the C-terminal fragment of antidiuretic 0.18 vs. 0.49±0.26 ng/ml, p=0.409). hormone (ADH), is a new biomarker that has been found to Conclusions Rather than reflecting a reduced risk for car- be elevated in several cardiovascular disorders and is related diovascular disorders, we consider that reduced copeptin with prognosis. Patients with obstructive sleep apnea dem- level is related with disturbed ADH secretion in obstructive onstrate a tendency to develop coronary and cerebral ath- sleep apnea patients. Therefore, it would not be advisable to erosclerotic disease. Our aim was to investigate copeptin measure copeptin levels in obstructive sleep apnea patients levels in untreated new diagnosed obstructive sleep apnea to determine cardiovascular risk, while this marker could be patients without manifest cardiovascular disorders in order valuable to demonstrate impairment in ADH TI - Low serum copeptin levels in patients with obstructive sleep apnea JF - Sleep and Breathing DO - 10.1007/s11325-013-0822-7 DA - 2013-02-14 UR - https://www.deepdyve.com/lp/springer-journals/low-serum-copeptin-levels-in-patients-with-obstructive-sleep-apnea-X7PYHDv047 SP - 1187 EP - 1192 VL - 17 IS - 4 DP - DeepDyve ER -