TY - JOUR
AU1 - Biswal, Basudev
AU2 - Aradhana, Aparna
AU3 - Mohanty, Mamata Devi
AU4 - Choudhury, Jasashree
AU5 - Behera, Braja Kishore
AU6 - Beura, Subhasree
AB - Tumor-induced osteomalacia (TIO), a rare paraneoplastic syndrome is seen in association with the overproduction of fibroblast growth factor-23 (FGF-23) by certain mesenchymal tumors in adults. In children, these phosphaturic mesenchymal tumors produce features of rickets similar to TIO. This condition is characterized by elevated blood levels of FGF-23, low phosphate, low or normal active vitamin D, and high alkaline phosphatase. Though the removal of the tumor is curative; in cases where surgical resection is not possible, medical treatment is successful with phosphate and active vitamin D in the improvement of symptoms. The case of a child with features of rickets is presented here to illustrate the importance of identifying this rare condition and instituting appropriate intervention.
TI - Tumor-Induced Osteomalacia- Like Syndrome with Rickets and Infantile Hepatic Hemangioendothelioma
JF - Indian Journal of Pediatrics
DO - 10.1007/s12098-023-04612-x
DA - 2024-08-01
UR - https://www.deepdyve.com/lp/springer-journals/tumor-induced-osteomalacia-like-syndrome-with-rickets-and-infantile-WmLZM39kls
SP - 842
EP - 844
VL - 91
IS - 8
DP - DeepDyve
ER -