TY - JOUR AU1 - Kreiser, Wesley, R AU2 - Martin, Robert, A AB - Abstract A method was developed for determining theobromine and caffeine in cocoa and chocolate products by high pressure liquid chromatography. After a simple hot water extraction, both theobromine and caffeine were separated by using a reverse phase Cl s column and a mobile phase of methanol-water-acetic acid (20+ 79+1). Theobromine and caffeine were quantitated at 280 nm; average recoveries were 98.7 and 95.0%; and coefficients of variation were 2.31 and 3.91%, respectively. This content is only available as a PDF. © Journal of the Association of Official Analytical Chemists This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model) TI - High Pressure Liquid Chromatographic Determination of Theobromine and Caffeine in Cocoa and Chocolate Products JF - Journal of AOAC INTERNATIONAL DO - 10.1093/jaoac/61.6.1424 DA - 1978-11-01 UR - https://www.deepdyve.com/lp/oxford-university-press/high-pressure-liquid-chromatographic-determination-of-theobromine-and-WIv9f6owkp SP - 1424 EP - 1427 VL - 61 IS - 6 DP - DeepDyve ER -