TY - JOUR
AU - Siever,  Larry
AB - In contrast to what has been found in schizophrenia, SPD was not associated with significant alterations in prefrontal D1 receptor availability. Similar to previous schizophrenia findings, however, higher prefrontal D1 receptor availability was associated with poorer WM performance (as measured by the PASAT) in SPD. These findings suggest that schizophrenia and SPD may share a common pathophysiological feature related to prefrontal dopamine functioning that contributes to WM dysfunction, but that in SPD, alterations in D1 may occur only in a subset of individuals and/or to an extent that is minor relative to what occurs in schizophrenia.
TI - Prefrontal dopamine D1 receptors and working memory in schizotypal personality disorder: a PET study with ( 11 C)NNC112
JF - Psychopharmacology
DO - 10.1007/s00213-014-3566-6
DA - 2014-10-01
UR - https://www.deepdyve.com/lp/springer-journals/prefrontal-dopamine-d1-receptors-and-working-memory-in-schizotypal-VaS2E3OLIK
SP - 4231
EP - 4240
VL - 231
IS - 21
DP - DeepDyve
ER -