TY - JOUR
AU - HOSKINS, R. G.
AB - Abstract Studies on rats by the revolving cage method have shown that castration results in a marked decrease in voluntary activity. In one series of experiments (Hoskins, 1925) sixteen control and sixteen experimental animals were studied over a period of 120 days. From a group of about fifty young animals that had become accustomed to the apparatus sixteen pairs (mostly twins) were selected; these were well matched both as to weight and as to activity records over a preliminary period of 20 days. Then the more active of each pair was castrated, the age of the animal being about 70 days. Beginning at about the twelfth day, on the average, the activity of the castrated animals began to lag behind that of the controls. At the fiftieth day after operation, the activity of the control group was at its height, averaging approximately 15,000 yards a day, while that of the castrated group averaged about 3200 yards. At the end of 100 days the averages were about 6000 and 3100 yards, respectively. Numerous subsequent observations have confirmed these results. Directly or indirectly, therefore, the testes condition in an important way the spontaneous activity of the animals. Available data offer little in the way of explanation of such findings. Some observers have reported a slight depression of basal metabolism, but others have failed to corroborate this (Lusk, 1925). This content is only available as a PDF. Copyright © 1926 by The Endocrine Society
TI - STUDIES ON VIGOR. VII. THE FATIGABILITY OF CASTRATED RATS
JF - Endocrinology
DO - 10.1210/endo-10-1-56
DA - 1926-01-01
UR - https://www.deepdyve.com/lp/oxford-university-press/studies-on-vigor-vii-the-fatigability-of-castrated-rats-VGBY3kfEwH
SP - 56
EP - 63
VL - 10
IS - 1
DP - DeepDyve
ER -