TY - JOUR AU - Thorner, Michael, O. AB - Abstract Acromegaly was diagnosed in a 37-year-old woman with classical physical and biochemical findings; an enlarged sella on computed tomography suggested the presence of a pituitary macroadenoma. Radiologic evidence of a lung mass prompted radioimmunoassay of plasma growth hormone-releasing factor (7,500 pg/ml; normal < 100 pg/ml). After resection of a bronchial carcinoid, which stained positive for growth hormone-releasing factor, circulating growth hormone-releasing factor levels normalized. Subsequently, her clinical, biochemical, and radiologic evidence for acromegaly resolved. This case represents the first reported use of the human pancreatic growth hormone-releasing factor 1–40 radioimmunoassay to pre-operatively diagnose this rare etiology of acromegaly. This content is only available as a PDF. Author notes 1 The opinions expressed herein reflect only those of the authors and not necessarily those of the Department of Defense, the United States Air Force, or any other federal agency. The authors alone are responsible for the contents of this paper. Reprint & Copyright © by Association of Military surgeons of U.S., 1991 TI - Preoperative Diagnosis Of Acromegaly by Growth Hormone-Releasing Factor Radioimmunoassay JO - Military Medicine DO - 10.1093/milmed/156.7.375 DA - 1991-07-01 UR - https://www.deepdyve.com/lp/oxford-university-press/preoperative-diagnosis-of-acromegaly-by-growth-hormone-releasing-VG04RlvwJv SP - 375 EP - 378 VL - 156 IS - 7 DP - DeepDyve ER -