TY - JOUR
AU - HENN, MARY JO
AB - Abstract THE COMPOUND hexachlorophene (2,2'-dihydroxy-3,5,6-3',5'6'-hexachlorodiphenyl-methane) frequently referred to as G-11 or AT-7 and incorporated into liquid soap, has been studied extensively as an effective bactericidal agent in reducing the numbers of bacterial flora of the human skin. The studies on liquid soaps by Traub and his co-workers1 in 1944 and 1945, by Clark and others2 in 1947 and by Price and his colleagues3 in 1948 are informative and convincing. Seastone and Erickson4 made valuable studies and in 1949 compared the liquid and bar soaps as vehicles for hexachlorophene in the surgical scrub. Nungester, Thirlby and Vial5 in 1949 evaluated a bar soap containing this formula and concluded that a three minute scrub with such a soap was superior to the usual 10 minute surgical scrub. In spite of these excellent studies, it was difficult for our group at the University Hospital to accept this rather radical References 1. Traub, E. F.; Newhall, C. A., and Fuller, J. R.: The Value of a New Compound Used in Soap to Reduce the Bacterial Flora of the Human Skin , Surg., Gynec. & Obst. 79:205-216 ( (Aug.) ) 1944 2. New Cutaneous Bacteriocidal Agent Used in Soap , Arch. Dermat. & Syph. 52:385-388 ( (Nov.-Dec.) ) 1945. 3. Clark, D. G. C; Lockwood, J. S., and Lewit, E.: G-11 as an Antiseptic for Use in Surgical Scrubbing , Surgery 22:360-366 ( (Aug.) ) 1947. 4. Price, P. B., and Bonnett, A.: The Antibacterial Effects of G-5, G-11, and A-151 with Special Reference to Their Use in the Production of a Germicidal Soap , Surgery 24:542-554 ( (Sept.) ) 1948. 5. Seastone, C. V.: Observations on the Use of G-11 in the Surgical Scrub , Surg., Gynec. & Obst. 84:355-360 ( (March) ) 1947. 6. Seastone, C. V., and Erickson, T. C.: A Comparison of Solid and Liquid Soap as Vehicles for G-11 (Hexachlorophene) in the Surgical Wash , Surgery 25:290-296 ( (Feb.) ) 1949. 7. Nungester, W. J.; Thirlby, R. L., and Vial, A. B.: Evaluation of Hexachlorophene and Detergents as Substitutes for the Surgical Scrub , Surg., Gynec. & Obst. 88:639-642 ( (May) ) 1949. 8. The bar soap (dial®) containing 2 per cent hexachlorophene (G-11; AT-7) was supplied by Armour and Company. 9. Brown, W. E.; Gunderson, M. F.; Schwartz, P., and Wilder, V. M.: A Clinical and Bacteriological Study of Phemerol as a Skin Antiseptic , Surg., Gynec. & Obst. 78:173-180 ( (Feb.) ) 1944. 10. Formula 99, prepared by Armour and Company, is a liquid soap containing 1 per cent hexachlorophene without alcohol.
TI - EFFECTIVENESS OF SOAPS CONTAINING HEXACHLOROPHENE FOR THE SURGICAL SCRUB: Special Reference to Bar Soap
JF - A.M.A. Archives Surgery
DO - 10.1001/archsurg.1950.01250020877008
DA - 1950-11-01
UR - https://www.deepdyve.com/lp/american-medical-association/effectiveness-of-soaps-containing-hexachlorophene-for-the-surgical-V2EYFYhJAz
SP - 869
EP - 880
VL - 61
IS - 5
DP - DeepDyve
ER -