TY - JOUR
AU - MENDES, NELSON, F.
AB - The percentage and absolute numbers of thymos-dependent (T) and thymos-independent (B) peripheral blood lymphocytes, the in vitro response of lymphocytes to phytohemagglutinin (PHA), and the sensitization with 2,4 dinitrochlorobenzene (DNCB) was studied in 26 patients with hyperthyroidism due to Graves' disease. The results showed a normal percentage of both T and B cells and increased absolute numbers of total lymphocytes in patients compared with 30 healthy controls. The in vitro response to PHA was normal in most patients with the exception of 5 of them who showed an impaired response. All patients developed a reaction of delayed hypersensitivity to DNCB. Our study indicated that there is no general abnormality in cell-mediated immunity in Graves' disease. This content is only available as a PDF. Author notes Supported by Fundação de Amparo à Pesquisa do Estado de São Paulo, Coordenação do Aperfeiçoamento de Passoal de Nível Superior e Conselho Nacional de Pesquisas. Copyright © 1976 by The Endocrine Society
TI - Peripheral Blood T and B Lymphocytes, in Vitro Stimulation with Phytohemagglutinin, and Sensitization with 2,4-Dinitrochlorobenzene in Graves' Disease
JO - Journal of Clinical Endocrinology and Metabolism
DO - 10.1210/jcem-42-3-583
DA - 1976-03-01
UR - https://www.deepdyve.com/lp/oxford-university-press/peripheral-blood-t-and-b-lymphocytes-in-vitro-stimulation-with-UOTy9T1RaB
SP - 583
EP - 587
VL - 42
IS - 3
DP - DeepDyve
ER -