TY - JOUR
AU - Rydn, Lars
AB - 1076 Letters to the Editor and superoxide anion production and infarction and stroke increased significantly doi:10.1093/eurheartj/ehn117 Online publish-ahead-of-print 18 March 2008 increase in the synthesis of eNO, and anti- by insulin treatment. This proposal is sup- 2–4 inflammatory cytokines. In the light of ported by the recent observation that immu- Glucose, insulin, and these observations, it is interesting to note nosuppressive therapy is useful in the coronary heart disease: reply that insulin therapy may relate to a more management of congestive cardiac failure serious prognosis in patients with coronary that could, in part, be attributed to the fact We appreciate that our articles on potentially artery disease (CAD) and the risk of non- that CHD is associated with low-grade sys- negative effects of insulin treatment have fatal myocardial infarction and stroke temic inflammation. attracted interest that initiates a discussion increased significantly by insulin treatment on possible explanations to this seemingly while metformin was protective. These unexpected finding. We agree that the analy- References apparently paradoxical and negative results sis of inflammatory markers and cytokines 1. Goyal A, Mahaffey KW, Garg J, Nicolau JC, could be due to higher serum glucose levels may shed some further light on this issue. 
TI - Glucose, insulin, and coronary heart disease: reply
JO - European Heart Journal
DO - 10.1093/eurheartj/ehn117
DA - 2008-04-18
UR - https://www.deepdyve.com/lp/oxford-university-press/glucose-insulin-and-coronary-heart-disease-reply-UDdyTkQ9MS
SP - 1076
EP - 1077
VL - 29
IS - 8
DP - DeepDyve
ER -