TY - JOUR AU - Ramaiya, Nikhil AB - The role of FDG PET/CT in anal cancer is becoming increasingly important. At the time of initial staging, FDG PET/CT can detect the primary site of disease more frequently than CT, is sensitive for nodal and metastatic spread and alters staging in a significant number of patients. Indeed, the NCCN guidelines for anal cancer published in April 2012 recommend FDG PET/CT for therapy planning. Metabolic activity of primary anal cancer at presentation is a potential biomarker for predicting prognosis, treatment response and survival. More intensely FDG-avid primary malignancy is associated with a higher incidence of disease spread. Metabolic response following chemoradiotherapy is associated with improved survival. The aim of this paper is to provide an up-to-date pictorial review of FDG PET/CT in anal cancer at the time of staging and to illustrate its utility for determining response to therapy and detecting recurrent disease. TI - Anal carcinoma: FDG PET/CT in staging, response evaluation, and follow-up JF - Abdominal Radiology DO - 10.1007/s00261-012-9958-3 DA - 2012-09-26 UR - https://www.deepdyve.com/lp/springer-journals/anal-carcinoma-fdg-pet-ct-in-staging-response-evaluation-and-follow-up-TvcLtS8cCS SP - 728 EP - 735 VL - 38 IS - 4 DP - DeepDyve ER -