TY - JOUR AU - Plantinga, Nienke L. AB - Intensive Care Med (2021) 47:331–333 https://doi.org/10.1007/s00134-021-06359-5 LESS IS MORE IN INTENSIVE C ARE 1* 2 Bastiaan H. Wittekamp and Nienke L. Plantinga © 2021 Springer-Verlag GmbH Germany, part of Springer Nature Oral care in the intensive care unit (ICU) is a basic need, assessment, as opposed to VAP. Is oral care with chlo- but oral care regimens vary, ranging from daily tooth rhexidine not so safe and effective after all? brushing to applying antiseptics or antibiotics around the There are a few important side notes on these nega - clock. While tooth brushing may be considered a stand- tive effects. First, regarding oral mucosal side effects, ard procedure strategies with antiseptics or antibiotics CHX 2% is ten times as strong as concentrations that have gained more ground in the past decades because of are regularly used [4] and seems too aggressive for use their beneficial effect on ICU-acquired infections and, for in critically ill, intubated patients. In this respect “less is selective decontamination using antibiotics, also mortal- more”. Second, as to yet, it remains unknown how CHX ity [1–3]. mouthwash (0.12/0.20%) increases mortality; is it chemi- The most widely used antiseptic for oral hygiene in cal damage following micro-aspiration? TI - Less daily oral hygiene is more in the ICU: no JF - Intensive Care Medicine DO - 10.1007/s00134-021-06359-5 DA - 2021-02-08 UR - https://www.deepdyve.com/lp/pubmed-central/less-daily-oral-hygiene-is-more-in-the-icu-no-TiZ6MAjMYp SP - 331 EP - 333 VL - 47 IS - 3 DP - DeepDyve ER -