TY - JOUR AU - Stolte, Manfred AB - Int J Colorectal Dis (2007) 22:1445–1451 DOI 10.1007/s00384-007-0364-1 ORIGINAL ARTICLE Boswellia serrata extract for the treatment of collagenous colitis. A double-blind, randomized, placebo-controlled, multicenter trial Ahmed Madisch & Stephan Miehlke & Otto Eichele & Jenny Mrwa & Birgit Bethke & Eberhard Kuhlisch & Elke Bästlein & Georg Wilhelms & Andrea Morgner & Bernd Wigginghaus & Manfred Stolte Accepted: 3 July 2007 / Published online: 2 September 2007 Springer-Verlag 2007 Abstract placebo. Complete colonoscopy and histology were performed Background and aims The objective of this study was to before and after treatment. Clinical symptoms and quality of investigate the effect of Boswellia serrata extract (BSE) on life were assessed by standardized questionnaires and SF-36. symptoms, quality of life, and histology in patients with The primary endpoint was the percentage of patients with collagenous colitis. clinical remission after 6 weeks (stool frequency ≤3soft /solid Materials and methods Patients with chronic diarrhea and stools per day on average during the last week). Patients of the histologically proven collagenous colitis were randomized to placebo group with persistent diarrhea received open-label receiveeitheroralBSE 400mgthree times dailyfor6 weeks or BSE therapy for a further 6 weeks. Results Thirty-one patients were randomized; 26 patients were available for TI - Boswellia serrata extract for the treatment of collagenous colitis. A double-blind, randomized, placebo-controlled, multicenter trial JF - International Journal of Colorectal Disease DO - 10.1007/s00384-007-0364-1 DA - 2007-09-02 UR - https://www.deepdyve.com/lp/springer-journals/boswellia-serrata-extract-for-the-treatment-of-collagenous-colitis-a-T2VD02wMaE SP - 1445 EP - 1451 VL - 22 IS - 12 DP - DeepDyve ER -