TY - JOUR
AU1 - Furuzono, Tsutomu
AU2 - Sonoda, Kensaku
AU3 - Tanaka, Junzo
AB - A novel composite consisting of hydroxyapatite (HAp) microparticles covalently coupled onto a silicone sheet was developed. Initially, an acrylic acid (AAc) ‐grafted silicone sheet with a 16.7 μg/cm2 surface graft density was prepared by corona‐discharge treatment. The surface of sintered, spherical, carbonated HAp particles with an average diameter of 2.0 μm was subsequently modified with amino groups. The amino group surface density of the HAp particles was calculated to be approximately one amino molecule per 1.0 nm2 of particle surface area. These samples were characterized with Fourier transform infrared spectrometry and X‐ray photoelectron spectroscopy. After the formation of ammonium ionic bonds between both samples under aqueous conditions, they were reacted at 180°C for 6 h in vacuo to form covalent bonds through a solid‐phase condensation. The HAp particles were coupled to the AAc‐grafted silicone surface by a covalent linkage. Further improvements in the adhesive and bioactive properties of the HAp‐coated silicone material are expected. © 2001 John Wiley & Sons, Inc. J Biomed Mater Res 56: 9–16, 2001
TI - A hydroxyapatite coating covalently linked onto a silicone implant material
JF - Journal of Biomedical Materials Research
DO - 10.1002/1097-4636(200107)56:1<9::AID-JBM1073>3.3.CO;2-U
DA - 2001-07-01
UR - https://www.deepdyve.com/lp/wiley/a-hydroxyapatite-coating-covalently-linked-onto-a-silicone-implant-Se0Bwbm4Hx
SP - 9
EP - 16
VL - 56
IS - 1
DP - DeepDyve
ER -