TY - JOUR AB - Reactions 1563, p130 - 8 Aug 2015 Various toxicities: case report A 53-year-old woman developed flu-like symptoms following treatment with potassium iodide for fixed cutaneous sporotrichosis; itraconazole was subsequently administered with ensuing fever, vomiting and malaise [times to reaction onsets and outcomes not stated]. The woman with rheumatoid arthritis and diabetes mellitus started receiving oral saturated solution of potassium iodide, 5 drops 3 times daily, following diagnosis of fixed cutaneous sporotrichosis. After her initial dose, she developed intolerable flu-like symptoms and treatment was stopped. She was subsequently administered itraconazole 100mg twice daily [route not stated], yet after her second dose, she developed vomiting, fever and general malaise. Itraconazole was withdrawn, and liposomal amphotericin B was successfully initiated. Author comment: "Our patient developed flu-like symptoms and could not tolerate itraconazole perhaps due to drug (anti-diabetics) interaction. She refused further oral therapy of any kind despite adequate counseling." Mahajan VK, et al. Fixed cutaneous sporotrichosis treated with topical amphotericin B in an immune suppressed patient. Medical Mycology Case Reports 7: 23-25, Mar 2015 - India 803132606 0114-9954/15/1563-0001/$14.95 Adis © 2015 Springer International Publishing AG. All rights reserved Reactions 8 Aug 2015 No. 1563 TI - Itraconazole/potassium iodide JF - Reactions Weekly DO - 10.1007/s40278-015-4059-z DA - 2015-08-08 UR - https://www.deepdyve.com/lp/springer-journals/itraconazole-potassium-iodide-Sc0Vl6jrVy SP - 130 EP - 130 VL - 1563 IS - 1 DP - DeepDyve ER -