TY - JOUR AU - M. L. Landsman , G. Kwant , G. A. Mook , and W. G. Zijlstra AB - U.S.A. Light-absorbing , stability, spectral stabilization M. L. J. LSMAN, G. Labot’atory Chemical Physiology, G. A. W. G. University Groningen, Groningen, The Netherls G. A, W. G. , stability, spectral stabilization . J. Appl. Physiol. 40(4):575583. 1976. -The absorption spectrum depends on the nature the solvent medium on the dye concentration. Binding to plasma proteins causes the principal peaks in the absorption spectrum to shift about 25 nm toward the higher wavelengths. The much greater influence on the spectrum the dye concentration results from progressive aggregate formation with increasing concentration. solutions therefore do not follow Lambert-Beer’s law above 15 mgF (in plasma). solutions in plasma concentrated (1,000 mg+I) solutions in distilled water are stable for at least 4 h, In long-term experiments the optical density solutions in plasma as well as in distilled water generally diminishes, even in the dark. On the 7th day a new absorption maximum starts to appear at h = 900 nm, possibly caused by further aggregate formation leading to much larger particles. Spectral stabilization after injection a concentrated solution into the blood is most rapid when the dye is dissolved in distilled water. Spectral stabilization slows down with decreasing temperature. As rapid spectral TI - Light-absorbing properties, stability, and spectral stabilization of indocyanine green JF - Journal of Applied Physiology DA - 1976-04-01 UR - https://www.deepdyve.com/lp/the-american-physiological-society/light-absorbing-properties-stability-and-spectral-stabilization-of-Rm0kU32a0W VL - 40 IS - DP - DeepDyve ER -