TY - JOUR
AU - Jian, Baiyu
AB - Abstract The purpose of this work was to explore the potential application of MCNT as a colon-specific delivery system based on the enzyme responsive mechanism. A novel type of enzyme-sensitive colon-specific tablet (PM-tablet) based on pectin and multi-walled carbon nanotube (MCNT) was prepared by wet granulation tabletting method. The PM-tablet in the presence of pectinase exhibited enzyme degradation release and achieve a precise release in the colon. Our study had proposed a novel idea for the application of MCNT on the oral colon-specific drug delivery system.
TI - Enzyme-responsive mechanism based on multi-walled carbon nanotubes and pectin complex tablets for oral colon-specific drug delivery system
JF - Journal of Radioanalytical and Nuclear Chemistry
DO - 10.1007/s10967-019-06501-0
DA - 2019-05-01
UR - https://www.deepdyve.com/lp/springer-journals/enzyme-responsive-mechanism-based-on-multi-walled-carbon-nanotubes-and-RQXOTtnCqh
SP - 503
EP - 512
VL - 320
IS - 2
DP - DeepDyve
ER -