TY - JOUR
AU - Jha,, T.K.
AB - Abstract Allopurinol, at doses of 300 to 1,200 mg per day for at least 14 days, was tested on 17 hospital patients with confirmed kala-azar. 14 of these were considered “cured” on clinical grounds and eight of these were confirmed by the absence of amastigotes in the bone marrow. Four were not examined parasitologically and two remained infected. Before further clinical trials of allopurinol are undertaken it is important to assess the role of its metabolites. References Currie et al., 1978 Currie W.J.C. , Turner P. , Young J.H. . Evaluation of once a day allopurinol administration in man , British Journal of Pharmacology , 1978 , vol. 5 (pg. 90 - 91 ) Google Scholar Crossref Search ADS WorldCat Marr, 1977 Marr J.J. . Antileishmanial effect of allopurinol. II. Relationship of adenine metabolism in Leishmania species to the action of allopurinol , Journal of Infectious Diseases , 1977 , vol. 77 pg. 724 Google Scholar Crossref Search ADS WorldCat Pfaller and Marr, 1974 Pfaller M.A. , Marr J.J. . Antileishmanial effect of allopurinol , Antimicrobial Agents and Chemotherapy , 1974 , vol. 5 (pg. 469 - 472 ) Google Scholar Crossref Search ADS PubMed WorldCat This content is only available as a PDF.
TI - Evaluation of allopurinol in the treatment of kala-azar occurring in North Bihar, India
JF - Transactions of The Royal Society of Tropical Medicine and Hygiene
DO - 10.1016/0035-9203(83)90071-8
DA - 1983-01-01
UR - https://www.deepdyve.com/lp/oxford-university-press/evaluation-of-allopurinol-in-the-treatment-of-kala-azar-occurring-in-R9FEQwinLn
SP - 204
EP - 207
VL - 77
IS - 2
DP - DeepDyve
ER -