TY - JOUR
AU - Nordborg, Magnus
AB - Various expressions related to the length of a conserved haplotype around a polymorphism of known frequency are derived. We obtain exact expressions for the probability that no recombination has occurred in a sample or subsample. We obtain an approximation for the probability that no recombination that could give rise to a detectable recombination event (through the four-gamete test) has occurred. The probabilities can be used to obtain approximate distributions for the length of variously defined haplotypes around a polymorphic site. The implications of our results for data analysis, and in particular for detecting selection, are discussed.
TI - The Extent of Linkage Disequilibrium and Haplotype Sharing Around a Polymorphic Site
JO - Genetics
DO - 10.1093/genetics/165.1.437
DA - 2003-09-01
UR - https://www.deepdyve.com/lp/oxford-university-press/the-extent-of-linkage-disequilibrium-and-haplotype-sharing-around-a-R7Bfls0rA0
SP - 437
EP - 444
VL - 165
IS - 1
DP - DeepDyve
ER -