TY - JOUR AU - LEMAIRE, WILLIAM, J. AB - The cytosol of human ovarian tissues was observed to promote protein phosphorylation in the combined presence of Ca2+,1,2-diolein, and phosphatidylserine. Ca2+alone or lipid alone did not produce full activation of this protein kinase(s). The addition of human erythrocyte calmodulin to the assay mixture, in the presence or absence of Ca2+, had no effect on protein kinase activity. Phosphorylation of cytosol proteins ranging in mol wt from 10,000 to 200,000 was selectively increased by Ca2+ plus lipid. This protein kinase activity may play a crucial role in the intracellular transmission of the action of hormones affecting cellular Ca2+ flux and/or phospholipid metabolism. This content is only available as a PDF. Copyright © 1983 by The Endocrine Society TI - CALCIUM- AND LIPID-DEPENDENT PROTEIN PHOSPHORYLATION IN THE HUMAN OVARY JO - Journal of Clinical Endocrinology and Metabolism DO - 10.1210/jcem-57-4-872 DA - 1983-10-01 UR - https://www.deepdyve.com/lp/oxford-university-press/calcium-and-lipid-dependent-protein-phosphorylation-in-the-human-ovary-QYoOmcBqaz SP - 872 EP - 874 VL - 57 IS - 4 DP - DeepDyve ER -