TY - JOUR AU - Critchlow, Gail AB - Rationale: Reducing serotonin by the method of tryptophan depletion (TD) has led to increased aggression but experimental studies have not used female subjects. Objective: To evaluate the effects of TD on aggression in women in the late luteal phase of their menstrual cycle. Methods: Healthy women were recruited and randomly assigned to an amino acid drink either depleted or with a balanced amount of tryptophan. At 4.5 h later, they competed on the competitive reaction time task. Results: Women who had received the TD drink showed more behavioural aggression in response to provocation. Conclusion: Decreased serotonergic neurotransmission increases aggression in women as well as men. TI - Tryptophan depletion increases aggression in women during the premenstrual phase JF - Psychopharmacology DO - 10.1007/s002130100795 DA - 2001-08-08 UR - https://www.deepdyve.com/lp/springer-journals/tryptophan-depletion-increases-aggression-in-women-during-the-PwHbf3JLdK SP - 477 EP - 480 VL - 156 IS - 4 DP - DeepDyve ER -