TY - JOUR
AU - Faracci,, Rosalie
AB - Abstract A gas chromatographic method for the quantitative determination of glutethimide was developed. This method was applied to samples obtained from patients who were comatose because of acute glutethimide intoxication. The results obtained from this procedure were compared with those obtained by using an ultraviolet method. The patients’ clinical conditions were assessed and correlated with the blood concentrations of glutethimide. The samples were processed to isolate glutethimide, as well as its metabolites. The metabolites were separated using thin-layer chromatography and were checked for purity by both thin-layer and gas chromatography. This content is only available as a PDF. © 1968 The American Association of Clinical Chemists, Inc. This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model)
TI - Determination of Glutethimide (Doriden) and Its Metabolites in Biologic Specimens
JF - Clinical Chemistry
DO - 10.1093/clinchem/14.7.595
DA - 1968-07-01
UR - https://www.deepdyve.com/lp/oxford-university-press/determination-of-glutethimide-doriden-and-its-metabolites-in-biologic-PrsV85yHQ8
SP - 595
EP - 609
VL - 14
IS - 7
DP - DeepDyve
ER -