TY - JOUR AU - Huang, Ching-Cheng AB - A series of designed drug-release systems were prepared and established for clear moisture healing. These systems were designed to have an interpenetrating polymer network (IPN) structure, which contained a breathable polyurethane film, hydrocolloidlayer, and polyacrylate adhesive layer. Breathable polyurethane film (2000 g/m2/24 hr) with high moisture permeability was employed as a base for new drug-release systems or wound dressings. All drug-release systems having a polyurethane film-backed hydrocolloid acrylated adhesive layer showed an increase of water uptakes with increasing time. After 114 hours, high water uptakes of drug-release systems with 20% hydrocolloid components were observed in the values of 160, 1100, and 1870% for different additional hydrocolloid components of carboxymethylcellulose, sodium alginate, and carbomer U10, respectively. New drug-release systems of polyurethane film-backed hydrocolloid/adhesive layers could be designed and established for wound care managements. TI - Designed drug-release systems having various breathable polyurethane film-backed hydrocolloid acrylated adhesive layers for moisture healing JF - Bio-Medical Materials and Engineering DO - 10.3233/bme-141018 DA - 2014-11-01 UR - https://www.deepdyve.com/lp/ios-press/designed-drug-release-systems-having-various-breathable-polyurethane-P4BegX0FLj SP - 2081 EP - 2088 VL - 24 IS - 6 DP - DeepDyve ER -