TY - JOUR
AU - Ryan, T.J.
AB - British Journal of Dermatology (1986) 115, 117-118. Correspondence Subcnrneal pustular dertnatosis followed by pyoderma gangrenosutn MADAM, We were interested 10 read the recent case report by Marsden and Millard (Brhish Journal of Dermatology 1986, 114, 125) of pyoderma gangrcnosum, subcomeal pustular dermatosis and IgA paraproteinaemia. We have recently seen a remarkably similar patieni. In 1979, a 59-ycar-oId woman presented with a 6-month history of a widespread burning eruption. Examination revealed i cm flaccid, pus-filled blisters (Fig. ia) and multiple superficial erosions, measuring 1-5 cm in diameter (Fig. ib). Some of these erosions were crusted, while others showed central clearing with a scaling serpiginous border, surrounded by a halo of erythema. Both bullac and erosions were widely scattered but showed a predilection for the flexural areas, including the groin, axillae and submammary region; the face was spared. Healing occurred slowly without scarring but left very persistent pigmented marks. Investigations showed a slight neutropenia(WBC: 3 7 x io^/!;44"o polymorphs)andanESRof55 mm/ hour, but were otherwise normal. Immunoglobutins were not measured. Biopsies of the lesions showed superficial pustules covered by a thin layer of keratin with occasional acantholytic cells. Polymorph neutrophils were seen infiltrating both the dermis and epidermis, singly and in groups. 
TI - Subcorneal pustular dermatosis followed by pyoderma gangrenosum
JO - British Journal of Dermatology
DO - 10.1111/j.1365-2133.1986.tb06229.x
DA - 1986-07-01
UR - https://www.deepdyve.com/lp/oxford-university-press/subcorneal-pustular-dermatosis-followed-by-pyoderma-gangrenosum-OKcA0ohp4x
SP - 117
EP - 118
VL - 115
IS - 1
DP - DeepDyve
ER -