TY - JOUR AU1 - Alamneh, Endalkachew AU2 - Chalmers, Leanne AU3 - Bereznicki, Luke AB - Am J Cardiovasc Drugs (2016) 16:183–200 DOI 10.1007/s40256-016-0161-8 SYSTEMATIC REVIEW Suboptimal Use of Oral Anticoagulants in Atrial Fibrillation: Has the Introduction of Direct Oral Anticoagulants Improved Prescribing Practices? 1 1 1 • • Endalkachew A. Alamneh Leanne Chalmers Luke R. Bereznicki Published online: 10 February 2016 Springer International Publishing Switzerland 2016 Abstract countries; there has been limited impact to date on pre- Background and Objectives Atrial fibrillation (AF) and scribing practice. the associated risk of stroke are emerging epidemics Conclusion Available data from clinical practice suggest throughout the world. Suboptimal use of oral anticoagu- that suboptimal oral anticoagulant use in patients with AF lants for stroke prevention has been widely reported from and poor compliance with guidelines still remain com- observational studies. In recent years, direct oral antico- monplace despite transition to a new era of anticoagulation agulants (DOACs) have been introduced for thrombopro- featuring DOACs. phylaxis. We conducted a systematic literature review to evaluate current practices of anticoagulation in AF, phar- macologic features and adoption patterns of DOACs, their Key Points impacts on proportion of eligible patients with AF who receive oral anticoagulants, persisting challenges and The introduction of direct oral anticoagulants future prospects for optimal anticoagulation. (DOACs) TI - Suboptimal Use of Oral Anticoagulants in Atrial Fibrillation: Has the Introduction of Direct Oral Anticoagulants Improved Prescribing Practices? JF - American Journal of Cardiovascular Drugs DO - 10.1007/s40256-016-0161-8 DA - 2016-02-10 UR - https://www.deepdyve.com/lp/springer-journals/suboptimal-use-of-oral-anticoagulants-in-atrial-fibrillation-has-the-O0Ov0MsyhG SP - 183 EP - 200 VL - 16 IS - 3 DP - DeepDyve ER -