TY - JOUR
AU - MIGEON, CLAUDE, J.
AB - Abstract Medroxyprogesterone (oral or im) administered to normal adult males produced a decrease in the plasma levels of testosterone (T) but little or no change in those of androstenedione (Δ). This therapy did not modify significantly the metabolic clearance rates of T and Δ. Therefore, the blood production rates of these androgens reflected directly the changes in plasma concentrations of T and Δ. Four boys, 3–5 yr of age, with idiopathic sexual precocity had plasma concentrations of T and Δ in the range observed for normal adult males. Administration of medroxyprogesterone (im) decreased the plasma T concentration of 3 of the boys but had no effect on the fourth subject. This therapy did not modify plasma Δ concentration of the patients. This content is only available as a PDF. Author notes Supported by USPHS Research Grant AM-00180, Traineeship Grant T1-AM-5219, Research Career Award K6-AM-21, 855 (CJM), and the John Simon Guggenheim Foundation and Consejo Nacional de Investigaciones Cientificas y Tecnicas of Argentina (MAR). Copyright © 1968 by The Endocrine Society
TI - Effect of Treatment with Medroxyprogesterone Acetate (Provera) on Testicular Function
JF - Journal of Clinical Endocrinology and Metabolism
DO - 10.1210/jcem-28-5-679
DA - 1968-05-01
UR - https://www.deepdyve.com/lp/oxford-university-press/effect-of-treatment-with-medroxyprogesterone-acetate-provera-on-Ntf2Hy8ba0
SP - 679
EP - 684
VL - 28
IS - 5
DP - DeepDyve
ER -