TY - JOUR AU - AB - Asian Journal of Pharmaceutical Education and Research Vol -10, Issue-1, January- March 2021 ISSN:2278 7496 RESEARCH ARTICLE Impact Factor: 7.014 FORMULATION, DEVELOPMENT AND EVALUATION OF ABACAVIR SUSTAINED RELEASE MICROSPHERES Yogesh Shendey*, Manju Prajapati, Parul Mehta, J.P. Rai School of pharmacy, LNCT University, Bhopal (M.P.) *Corresponding Author’s E mail: pshendey26@gmail.com Received 19 Nov. 2020; Revised 28 Nov 2020; Accepted 17 Dec. 2020, Available online 10 January 2021 Cite this article as: Shendey Y, Prajapati M, Mehta P, Rai JP. Formulation, Development and Evaluation of Abacavir Sustained Release Microspheres. Asian Journal of Pharmaceutical Education and Research. 2021; 10(1): 121-130. https://dx.doi.org/10.38164/AJPER/10.1.2021.121-130 ABSTRACT The purpose of this study was to develop and evaluate Abacavir loaded mucoadhesive microsphere for sustained drug release at the gastric mucosa. In present investigation Chitosan microspheres of Abacavir were prepared by using ionotropic gelation method. Different formulations F1 to F6 were prepared using varying amount of polymers like chitosan and TPP. The prepared and evaluated for Percentage yield, stability of microspheres, drug entrapment mean particle size, zeta potential and In vitro drug release study. Percentage yield of different formulation was determined by weighing the microspheres after drying. The percentage yield of different formulation was in range of 63.32±0.45–72.23±0.54%. The TI - FORMULATION, DEVELOPMENT AND EVALUATION OF ABACAVIR SUSTAINED RELEASE MICROSPHERES JF - Asian Journal of Pharmaceutical Education and Research DO - 10.38164/ajper/10.1.2021.121-130 DA - 2021-01-10 UR - https://www.deepdyve.com/lp/unpaywall/formulation-development-and-evaluation-of-abacavir-sustained-release-Nhq49Qm5Bk DP - DeepDyve ER -