TY - JOUR
AU - Guichard, J.P.
AB - This Article Figures Only Full Text Full Text (PDF) All Versions of this Article: ajnr.A0948v1 29/5/883 most recent Alert me when this article is cited Alert me if a correction is posted Citation Map Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by Neves, F. Articles by Guichard, J.P. Search for Related Content PubMed PubMed Citation Articles by Neves, F. Articles by Guichard, J.P. Hotlight (NEW!) What's Hotlight? American Journal of Neuroradiology 29:883-889, May 2008 © 2008 American Society of Neuroradiology HEAD & NECK Head and Neck Paragangliomas: Value of Contrast-Enhanced 3D MR Angiography F. Neves a , L. Huwart a , G. Jourdan a , D. Reizine a , P. Herman b , E. Vicaut c and J.P. Guichard a a Department of Neuroradiology, Groupe Hospitalier Lariboisière-Fernand-Widal AP-HP, Paris, France b Department of Otorhinolaryngology, Groupe Hospitalier Lariboisière-Fernand-Widal AP-HP, Paris, France c Department of Statistics, Groupe Hospitalier Lariboisière-Fernand-Widal AP-HP, Paris, France Please address correspondence to Jean-Pierre Guichard, MD, Service de Neuroradiologie, Hôpital Lariboisière, 2 rue Ambroise Paré, 75010 Paris, France; e-mail: jean-pierre.guichard@lrb.ap-hop-paris.fr BACKGROUND AND PURPOSE: A rapid and accurate MR imaging technique would be beneficial to assess paragangliomas in the head and neck and to distinguish them from other lesions. The purpose of this study was to determine whether the combination of elliptic centric contrast-enhanced MR angiography (CE-MRA) and unenhanced and enhanced spin-echo imaging (conventional MR imaging) is more accurate than conventional MR imaging alone to assess paragangliomas in the head and neck. MATERIALS AND METHODS: Three radiologists retrospectively and independently reviewed CE-MRA and conventional MR imaging in 27 patients with suspected paragangliomas. The overall image quality and the probability of paraganglioma were recorded. The results of each technique and their combination were analyzed for sensitivity and specificity. Receiver operating characteristic (ROC) analyses were performed by using histologic analysis, imaging, and/or clinical findings as the reference standard. RESULTS: Forty-six lesions were found in 27 patients. In the assessment of paragangliomas, the combination of conventional MR imaging and CE-MRA was significantly superior to conventional MR imaging alone. Sensitivity and specificity respectively were the following: for CE-MRA, 100% and 94%; and for conventional MR imaging, 94% and 41%. The specificity of CE-MRA was significantly higher than that of conventional MR imaging ( P = .004). There was good-to-excellent interobserver agreement for the paraganglioma probability with CE-MRA (nonweighted , 0.67–0.77), whereas there was fair-to-good interobserver agreement with conventional MR imaging (nonweighted , 0.50–0.65). CONCLUSION: In combination with conventional MR imaging, CE-MRA yields an excellent diagnostic value for the assessment of head and neck paragangliomas; hence, the 2 techniques should be regarded as complementary. Home Subscribe Author Instructions Submit Online Search the AJNR Archives Feedback Help Copyright © 2010 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X
TI - Head and Neck Paragangliomas: Value of Contrast-Enhanced 3D MR Angiography
JF - American Journal of Neuroradiology
DO - 10.3174/ajnr.A0948
DA - 2008-05-01
UR - https://www.deepdyve.com/lp/american-journal-of-neuroradiology/head-and-neck-paragangliomas-value-of-contrast-enhanced-3d-mr-Ne0SkhPHnB
VL - 29
IS - 5
DP - DeepDyve
ER -