TY - JOUR AU - Mackowiak, Philip A. AB - ANSWER TO PHOTO QUIZ Philip A. Mackowiak, Section Editor (See page 1834 for Photo Quiz) Figure 1. Micrograph showing plasma cells in a CSF specimen from a lumbar puncture Diagnosis: West Nile virus meningoencephalitis with acute have also been case reports of CSF plasmacytosis with other flaccid paralysis and parkinsonism. viral meningoencephalitidites, such as infections with entero- CSF revealed significant plasmacytosis (plasma cell percent- virus, Coxsackie virus, measles virus, mumps virus, HIV, and age, 40%) and moderate pleocytosis (figure 1). CSF was positive herpes zoster virus [5, 6]. However, these infections are only for West Nile virus IgM antibodies by ELISA capture technique, associated with mild CSF plasmacytosis (plasma cell percentage, which is pathognomic for diagnosis [1, 2]. CSF studies for 1%–6%). CSF plasmacytosis has also been rarely reported in herpes simplex virus, varicella zoster virus, cytomegalovirus, cases of neuroborreliosis, neurosyphilis, tuberculous meningi- cryptococci, Borrelia burgdorferi, and Ehrlichia species were per- tis, and neurocysticercosis [7, 8] formed, as well as culture for mycobacteria, and all results were Our patient’s fever resolved, and his mental status returned negative. to normal after 2 days. His parkinsonism symptoms gradu- CSF plasmacytosis is distinctly unusual. It has been reported ally lessened but still TI - A Man with Fever, Headache, and Confusion JO - Clinical Infectious Diseases DO - 10.1086/426087 DA - 2004-12-15 UR - https://www.deepdyve.com/lp/oxford-university-press/a-man-with-fever-headache-and-confusion-LW9obcWmmN SP - 1856 EP - 1857 VL - 39 IS - 12 DP - DeepDyve ER -