TY - JOUR AU1 - Whorton, C. Merrill AU2 - Yount, Ernest AU3 - Jones, Ralph AU4 - Craige, Branch AU5 - Alving, Alf S. AU6 - Pullman, Theodore N. AU7 - Craige, Branch AU8 - Eichelberger, Lillian AB - III. CLINICAL ASPECTS C. MERRILL WHORTON, ERNEST YOUNT, JR., RALPH JONES, JR., ALF S. ALVING, THEODORE N. PULLMAN, BRANCH CRAIGE, JR., AND LILLIAN EICHELBERGER The Malarial Research Unit, Department of Medicine, University of Chicago The purpose of this paper is to de­ volunteered for the clinical testing of scribe certain clinical aspects of infec­ new antimalarial drugs. Some of the tions with the newly isolated Chesson patients were given suppressive drugs strain of Plasmodium vivax. This strain during the prepatent] period, but the majority were untreated until the ap­ of malaria probably originated in New Guinea in 1944. We have studied it pearance of the primary attack. The history of sporozoite-induced infections under controlled conditions in 195 spo­ rozoite-induced infections in healthy was studied in segments consisting of volunteers at the Illinois State Peniten­ the primary attack and successive re­ tiary, at Joliet, 111., and in 125 tropho­ lapses. Almost all malarial attacks were zoite-induced* infections in psychotic brief, because therapeutic trials were patients at the Manteno State Hospital, usually begun early. Manteno, Ill. Trophozoite-induced infections were studied in white, male, psychotic pa­ tients, who received malaria for thera­ MATERIAL peutic purposes. These subjects served Sporozoite-induced infections* were as TI - The Chesson Strain of Plasmodium Vivax Malaria JF - The Journal of Infectious Diseases DO - 10.1093/infdis/80.3.237 DA - 1947-05-01 UR - https://www.deepdyve.com/lp/oxford-university-press/the-chesson-strain-of-plasmodium-vivax-malaria-LQt80N58C0 SP - 237 EP - 249 VL - 80 IS - 3 DP - DeepDyve ER -