TY - JOUR
AU1 - Boukhrissa, Houda
AU2 - Mechakra, Saleh
AU3 - Mahnane, Abbes
AU4 - Boussouf, Nadir
AU5 - Gasmi, Abdelkader
AU6 - Lacheheb, Abdelmadjid
AB - Hepatitis E virus (HEV) is recognized worldwide as the leading cause of orofecal-transmitted hepatitis. However, blood transmission has been increasingly implicated in recent years raising health concerns. In Algeria, updated prevalence data are lacking. We aimed to determine the prevalence of anti-HEV antibodies in the sera of volunteer blood donors from the Setif region in eastern Algeria. A total of 434 Samples were analyzed for anti-HEV IgG and IgM antibodies using an enzyme-linked immunosorbent assay (Wantai). Logistic regression modelling was used to identify associated risk factors. The IgG seroprevalence rate was 17.05%. Seven sera (0.16%) were weakly positive for IgM. No HEV RNA was detected. The IgG prevalence was significantly correlated with increasing age (p < 1p.1000). Our data demonstrate a relatively high prevalence of anti-HEV IgG, indicating a possible risk of HEV blood transmission which requires vireamic seroprevalence studies to assess the real risk.
TI - Seroprevalence of hepatitis E virus among blood donors in eastern Algeria
JF - Tropical Doctor
DO - 10.1177/00494755221112212
DA - 2022-10-01
UR - https://www.deepdyve.com/lp/sage/seroprevalence-of-hepatitis-e-virus-among-blood-donors-in-eastern-LQs0AwVGat
SP - 479
EP - 483
VL - 52
IS - 4
DP - DeepDyve
ER -