TY - JOUR AU1 - Novindra, Qanita Adzkia AU2 - Alifah, Fildzah Ghaisani AU3 - Syariafah, Nadia Alfi AU4 - AB - Parkinson's disease (PD) is a neurodegenerative disease that cannot be cured with clinical manifestations in the form of disturbances in motor movement. Currently the diagnosis of Parkinson's disease is still based on motor symptoms that arise. Early detection of PD is needed so that patients will receive early treatment to prevent pathogenesis of neuronal damage in the substantia nigra. Based on research, it is known that the symptoms of intestinal dysfunction appear 5-7 years before motor problems occur in PD patients. The onset of intestinal dysfunction is related to an imbalance in the composition of the intestinal microbiota (GM). The aim of this literature review is to conduct a literature study regarding the relationship between GM composition and the pathogenesis of Parkinson's disease as a basis for early detection of Parkinson's disease. The method used in this literature review process is the PRISMA method, where from the 261 initial sources that the author has obtained in accordance with the keywords using the Boolean method, 229 sources are excluded because they do not meet the inclusion criteria set by the author. From the results and discussion, it was found that bacterial dysbiosis in the gastrointestinal tract is a process that TI - EPSON (EARLY DETECTION FOR PARKINSON DISEASE) TINJAUAN PUSTAKA DISBIOSIS GUT MICROBIAL SEBAGAI POTENSI DETEKSI DINI PARKINSON MELALUI PEMERIKSAAN FESES JF - Al-Iqra Medical Journal : Jurnal Berkala Ilmiah Kedokteran DO - 10.26618/aimj.v4i1.4980 DA - 2021-03-06 UR - https://www.deepdyve.com/lp/unpaywall/epson-early-detection-for-parkinson-disease-tinjauan-pustaka-disbiosis-JwRnEpO0EE DP - DeepDyve ER -