TY - JOUR AU - Zhu, Timothy C. AB - Determination of in-vivo tissue optical properties for anal photodynamic therapy (PDT) is challenging due to the light integrating-sphere effect in an enclosed cylindrical cavity. We developed a model for optical properties determination for anal PDT from measurements of light fluence rate inside a cylindrical cavity submerged in tissue-mimicking liquid phantoms. Measurements are performed in a set of phantoms with known optical properties (a = 0.1-0.9 cm-1) and (s’ = 5.5-16.5 cm-1) and the primary and scatter light fluence rates are determined. We developed a forward empirical model to relate scatter light fluence rate measured in an enclosed cylindrical geometry to the surrounding tissue optical properties in tissue-simulating liquid phantoms. TI - Determination of in-vivo tissue optical properties for anal photodynamic therapy JF - Proceedings of SPIE DO - 10.1117/12.2525624 DA - 2019-08-07 UR - https://www.deepdyve.com/lp/spie/determination-of-in-vivo-tissue-optical-properties-for-anal-JlkuGGiKdO SP - 11070BI EP - 11070BI-5 VL - 11070 IS - DP - DeepDyve ER -