TY - JOUR
AU - Sepahdari, Ali
AB - Purpose Radiation treatment planning is typically based on the identification of a gross tumor volume (GTV) using computed tomography (CT). The clinical implementation of an integrated MRI-radiation therapy delivery unit allows for a strict compar- ison of CT- and MRI-derived GTVs for head and neck cancer. Materials and methods Twenty-six consecutive patients with squamous cell carcinoma of the head and neck were selected and planned for intensity-modulated radiotherapy (IMRT) on a novel tri- Co teletherapy system equipped with a 0.35 T MRI (ViewRay Incorporated, Oakwood Village, OH). All patients had measurable disease. Pre-treatment MRIs were imported into a contouring interface where the primary GTV were assessed and compared to those obtained from a registered CT with the patient in the identical position and immobilization apparatus. 3 3 3 Results The median GTV as derived from the CT and MRI was 27.2 cm (range 3.8 to 155.0 cm ) and 34.9 cm (range, 5.0 to 189.5 cm ), respectively (p = 0.01). The MRI-derived GTV was larger than the CT-derived GTV in 21 of the 26 cases and was smaller in the remaining 5 cases. Among the 21 cases where the MRI-derived GTV was larger, the median difference in absolute 
TI - Comparison between CT- and MRI-derived head and neck cancer target volumes using an integrated MRI-tri-60Co teletherapy device
JF - Journal of Radiation Oncology
DO - 10.1007/s13566-017-0337-0
DA - 2018-01-04
UR - https://www.deepdyve.com/lp/springer-journals/comparison-between-ct-and-mri-derived-head-and-neck-cancer-target-JYpgHXyPST
SP - 147
EP - 155
VL - 7
IS - 2
DP - DeepDyve
ER -