TY - JOUR AU - AB - NEPALESE HEART JOURNAL Dr. Shyam Regmi* Introduction A device to plug holes in the heart without open-heart surgery has been available for a decade. James Lock, M.D., chief cardiologist at Children’s Hospital Boston, developed his clamshell occluder for that purpose and also developed the CardioSEAL StarFlex, a newer model of that device. The StarFlex allows for the umbrella device to center itself to plug larger holes. "This device is not only effective in children, but can also be used in teenagers and young adults,” according to Douglas Moodie, M.D., M.S., chairman, Division of Pediatrics, Cleveland Clinic Children's Hospital in Cleveland, OH, “Short term follow-up studies are very encouraging. Such devices have “the potential to be as good as surgery without many of the risks inherent in open heart surgery,” says Andrew Lashus, M,D., Cook Children’s Medical Center. Fort Worth, TX, who is principal investigator on a phase III clinical trial of the CardioSEAL. StarFlex sanetioned by the Food and Drug Administration. But some hospitals favor another device, the Amplatzer. Arno Zaritsky, chairman of the department of pediatrics at Children’s Hospital of The King’s Daughters Health System in Norfolk, VA, says, “Our pediatric cardiologists participate in trials using the Amplatzer TI - Device Closure in Congenital Heart Disease JF - Nepalese Heart Journal DO - 10.3126/njh.v4i1.26151 DA - 2006-11-30 UR - https://www.deepdyve.com/lp/unpaywall/device-closure-in-congenital-heart-disease-JWr3vWM3aO DP - DeepDyve ER -