TY - JOUR
AU - Prineas, Ronald J.
AB - 32 8 Letters to trie Editor the data are more inconsistent than definitive" seen in epidemiologic studies of unselected pop- (2). Two recent, large-scale epidemiologic studies ulations with a wider range of blood pressure and add to the inconsistency and similarly conclude glucose tolerance. In contrast to the studies cited that insulin does not have a major role as a by Jarrett (3, 4), population-based studies have determinant of blood pressure/hypertension (3, shown that insulin-dependent diabetics have 4). However, it is clinical practice that provides higher systolic and diastolic blood pressure than the strongest evidence against insulin as a deter- their nondiabetic sibling controls (5). Thus, the minant of blood pressure. In insulin-dependent results of clinic-based studies must be interpreted diabetics, blood pressure levels were similar in with caution. patients and sibling controls (5) and in patients The strongest argument against an insulin/ with normal albumin excretion the prevalence of blood pressure link is, in fact, made by some hypertension was almost exactly the same as that observational studies which have been inconsis- in the general population (6). Such patients spend tent in noting such a relation (6). It should not a large proportion of their life with peripheral 
TI - THE AUTHORS REPLY
JF - American Journal of Epidemiology
DO - 10.1093/oxfordjournals.aje.a116093
DA - 1991-08-01
UR - https://www.deepdyve.com/lp/oxford-university-press/the-authors-reply-JS0keNJxnv
SP - 328
EP - 329
VL - 134
IS - 3
DP - DeepDyve
ER -