TY - JOUR AU - Dawson, Dana AB - 822 Image Focus IMAGE FOCUS doi:10.1093/ehjci/jex049 Online publish-ahead-of-print 31 March 2017 .................................................................................................................................................... 1 1 1,2 1,2 1,2 Michalis Koullouros *, Tarak A.M. Chouari , Andrew Stewart , Keith Kerr , and Dana Dawson 1 2 University of Aberdeen, Suttie Centre, Foresterhill, AB252ZD, Aberdeen, UK; and Aberdeen Royal Infirmary, Foresterhill, AB252ZD, Aberdeen, UK * Corresponding author. Tel: 1447823323825; Fax: 1441224550692. E-mail: m.koullouros@nhs.net A 32-year-old woman presented with an 8-week history of increasing dyspnoea and peripheral oedema. Electrocardiogram (ECG) showed junc- tional bradycardia (54 bpm) with left axis deviation, poor R-wave progression and T-wave inversion in precordial leads (Panel A). The NTpro-BNP was 1900 pg/mL. Echocardiography showed a normal size left ventricle (LV) with good systolic function, a flat interventricular septum, dilated right ventricle (RV) with severe tricuspid regurgitation (TR) and estimated pulmonary artery pressure of 25–30 mmHg, bi-atrial dilatation (Panels B and C), with an increased transmitral E-wave velocity and steep deceleration time (Panel D). Bubble contrast detected no intra-cardiac shunt (Panel E). Cardiac catheterization was unremarkable. A pacing wire placed in the right atrium (RA) confirmed electrically silent atria. Invasive studies re- vealed left and right ventricular end-diastolic pressures (LVEDP¼ 26 mmHg, RVEDP¼ 27 mmHg) equalization, with a typical TI - Isolated cardiac desminopathy JF - European Heart Journal – Cardiovascular Imaging DO - 10.1093/ehjci/jex049 DA - 2017-07-01 UR - https://www.deepdyve.com/lp/oxford-university-press/isolated-cardiac-desminopathy-JQIw3AsX0S SP - 822 EP - 822 VL - 18 IS - 7 DP - DeepDyve ER -